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Gene: DLL1 (delta like canonical Notch ligand 1) Homo sapiens
Symbol: DLL1
Name: delta like canonical Notch ligand 1
CRRD ID: 733842
Description: Exhibits Notch binding activity and Tat protein binding activity. Involved in Notch signaling pathway; negative regulation of interleukin-10 production; and neuronal stem cell population maintenance. Predicted to localize to adherens junction; apical plasma membrane; and membrane raft. Biomarker of temporal arteritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Delta; delta-like 1 (Drosophila); delta-like 1 protein; delta-like protein 1; DELTA1; DL1; drosophila Delta homolog 1; H-Delta-1; NEDBAS
Mus musculus (house mouse) : Dll1 (delta like canonical Notch ligand 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dll1 (delta like canonical Notch ligand 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dll1 (delta like canonical Notch ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DLL1 (delta like canonical Notch ligand 1)
Canis lupus familiaris (dog) : DLL1 (delta like canonical Notch ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dll1 (delta like canonical Notch ligand 1)
Sus scrofa (pig) : DLL1 (delta like canonical Notch ligand 1)
Chlorocebus sabaeus (African green monkey) : DLL1 (delta like canonical Notch ligand 1)
Heterocephalus glaber (naked mole-rat) : Dll1 (delta like canonical Notch ligand 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl6170,282,206 - 170,306,565 (-)EnsemblGRCh38hg38GRCh38
GRCh386170,282,200 - 170,291,078 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376170,591,288 - 170,599,815 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366170,433,219 - 170,441,622 (-)NCBINCBI36hg18NCBI36
Build 346170,508,932 - 170,517,112NCBI
Celera6171,388,861 - 171,397,261 (-)NCBI
Cytogenetic Map6q27NCBI
HuRef6168,098,039 - 168,106,439 (-)NCBIHuRef
CHM1_16170,851,870 - 170,860,273 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DLL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733842
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.