Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ppm1b (protein phosphatase 1B, magnesium dependent, beta isoform) Mus musculus
Analyze
Symbol: Ppm1b
Name: protein phosphatase 1B, magnesium dependent, beta isoform
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Involved in N-terminal protein myristoylation and protein dephosphorylation. Localizes to the cytosol and membrane. Is expressed in several structures, including blastocyst; early embryo; gonad; liver; and lung. Orthologous to human PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC106489; PP2C-beta; PP2CB; protein phosphatase 1B; protein phosphatase 2C isoform beta
Orthologs:
Homo sapiens (human) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent, 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Canis lupus familiaris (dog) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Sus scrofa (pig) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
more info ...
Related Pseudogenes: Gm7895  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1784,956,741 - 85,023,991 (+)Ensembl
GRCm381784,956,741 - 85,023,992 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371785,356,081 - 85,423,332 (+)NCBIGRCm37mm9NCBIm37
MGSCv361784,866,341 - 84,925,447 (+)NCBImm8
Celera1789,319,953 - 89,386,219 (+)NCBICelera
Cytogenetic Map17 E4NCBI
cM Map1755.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ppm1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733847
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.