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Gene: Ppm1b (protein phosphatase 1B, magnesium dependent, beta isoform) Mus musculus
Symbol: Ppm1b
Name: protein phosphatase 1B, magnesium dependent, beta isoform
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Involved in N-terminal protein myristoylation and protein dephosphorylation. Localizes to the cytosol and membrane. Is expressed in several structures, including blastocyst; early embryo; gonad; liver; and lung. Orthologous to human PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC106489; PP2C-beta; PP2CB; protein phosphatase 1B; protein phosphatase 2C isoform beta
Homo sapiens (human) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent, 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Canis lupus familiaris (dog) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1b (protein phosphatase, Mg2+/Mn2+ dependent 1B)
Sus scrofa (pig) : PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B)
more info ...
Related Pseudogenes: Gm7895  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1784,956,741 - 85,023,991 (+)Ensembl
GRCm381784,956,741 - 85,023,992 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371785,356,081 - 85,423,332 (+)NCBIGRCm37mm9NCBIm37
MGSCv361784,866,341 - 84,925,447 (+)NCBImm8
Celera1789,319,953 - 89,386,219 (+)NCBICelera
Cytogenetic Map17 E4NCBI
cM Map1755.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ppm1b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733847
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.