Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cdh23 (cadherin 23 (otocadherin)) Mus musculus
Analyze
Symbol: Cdh23
Name: cadherin 23 (otocadherin)
Description: Predicted to have several functions, including cadherin binding activity; protein N-terminus binding activity; and protein homodimerization activity. Involved in several processes, including animal organ morphogenesis; righting reflex; and sensory perception of sound. Localizes to several cellular components, including the cochlear hair cell ribbon synapse; photoreceptor ribbon synapse; and stereocilium tip. Used to study Usher syndrome type 1D and autosomal recessive nonsyndromic deafness 12. Human ortholog(s) of this gene implicated in Usher syndrome type 1D; autosomal recessive nonsyndromic deafness; autosomal recessive nonsyndromic deafness 12; and pituitary adenoma. Is expressed in several structures, including brain; genitourinary system; lung; sensory organ; and thymus. Orthologous to human CDH23 (cadherin related 23); PARTICIPATES IN auditory mechanotransduction pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930542A03Rik; age related hearing loss 1; ahl; ahl1; bob; bobby; bus; bustling; cadherin-23; mdfw; modifier of deaf waddler; nmf112; nmf181; nmf252; otocadherin; sals; USH1D; v; waltzer
Orthologs:
Homo sapiens (human) : CDH23 (cadherin related 23)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdh23 (cadherin-related 23)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh23 (cadherin related 23)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH23 (cadherin related 23)
Canis lupus familiaris (dog) : CDH23 (cadherin related 23)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh23 (cadherin related 23)
Sus scrofa (pig) : CDH23 (cadherin related 23)
Chlorocebus sabaeus (African green monkey) : CDH23 (cadherin related 23)
Heterocephalus glaber (naked mole-rat) : Cdh23 (cadherin related 23)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1060,302,748 - 60,696,490 (-)EnsemblGRCm38mm10GRCm38
GRCm381060,302,748 - 60,696,513 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371059,766,022 - 60,159,238 (-)NCBIGRCm37mm9NCBIm37
MGSCv361059,698,731 - 60,052,690 (-)NCBImm8
Celera1061,400,142 - 61,796,629 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1030.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdh23
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733852
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.