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Gene: Cdh23 (cadherin 23 (otocadherin)) Mus musculus
Symbol: Cdh23
Name: cadherin 23 (otocadherin)
Description: Predicted to have several functions, including cadherin binding activity; protein N-terminus binding activity; and protein homodimerization activity. Involved in several processes, including animal organ morphogenesis; righting reflex; and sensory perception of sound. Localizes to several cellular components, including the cochlear hair cell ribbon synapse; photoreceptor ribbon synapse; and stereocilium tip. Used to study Usher syndrome type 1D and autosomal recessive nonsyndromic deafness 12. Human ortholog(s) of this gene implicated in Usher syndrome type 1D; autosomal recessive nonsyndromic deafness; autosomal recessive nonsyndromic deafness 12; and pituitary adenoma. Is expressed in several structures, including brain; genitourinary system; lung; sensory organ; and thymus. Orthologous to human CDH23 (cadherin related 23); PARTICIPATES IN auditory mechanotransduction pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930542A03Rik; age related hearing loss 1; ahl; ahl1; bob; bobby; bus; bustling; cadherin-23; mdfw; modifier of deaf waddler; nmf112; nmf181; nmf252; otocadherin; sals; USH1D; v; waltzer
Homo sapiens (human) : CDH23 (cadherin related 23)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdh23 (cadherin-related 23)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh23 (cadherin related 23)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH23 (cadherin related 23)
Canis lupus familiaris (dog) : CDH23 (cadherin related 23)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh23 (cadherin related 23)
Sus scrofa (pig) : CDH23 (cadherin related 23)
Chlorocebus sabaeus (African green monkey) : CDH23 (cadherin related 23)
Heterocephalus glaber (naked mole-rat) : Cdh23 (cadherin related 23)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1060,302,748 - 60,696,490 (-)EnsemblGRCm38mm10GRCm38
GRCm381060,302,748 - 60,696,513 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371059,766,022 - 60,159,238 (-)NCBIGRCm37mm9NCBIm37
MGSCv361059,698,731 - 60,052,690 (-)NCBImm8
Celera1061,400,142 - 61,796,629 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1030.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cdh23
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733852
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.