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Gene: DGKZ (diacylglycerol kinase zeta) Homo sapiens
Symbol: DGKZ
Name: diacylglycerol kinase zeta
Description: Exhibits diacylglycerol kinase activity; lipid kinase activity; and protein C-terminus binding activity. Involved in several processes, including diacylglycerol metabolic process; mitotic G1 DNA damage checkpoint; and positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity. Localizes to the lamellipodium and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DAG kinase zeta; DAGK5; DAGK6; DGK-ZETA; diacylglycerol kinase, zeta 104kDa; diglyceride kinase zeta; hDGKzeta
Mus musculus (house mouse) : Dgkz (diacylglycerol kinase zeta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dgkz (diacylglycerol kinase zeta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgkz (diacylglycerol kinase zeta)
Pan paniscus (bonobo/pygmy chimpanzee) : DGKZ (diacylglycerol kinase zeta)
Canis lupus familiaris (dog) : DGKZ (diacylglycerol kinase zeta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgkz (diacylglycerol kinase zeta)
Sus scrofa (pig) : DGKZ (diacylglycerol kinase zeta)
more info ...
Related Pseudogenes: DGKZP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1146,332,905 - 46,380,554 (+)Ensembl
GRCh381146,332,905 - 46,380,554 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371146,354,455 - 46,402,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361146,311,315 - 46,358,680 (+)NCBINCBI36hg18NCBI36
Build 341146,323,562 - 46,358,680NCBI
Celera1146,502,317 - 46,549,682 (+)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1146,061,412 - 46,109,062 (+)NCBIHuRef
CHM1_11146,352,750 - 46,400,540 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DGKZ
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733860
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.