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Gene: Hes3 (hes family bHLH transcription factor 3) Mus musculus
Symbol: Hes3
Name: hes family bHLH transcription factor 3
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in in utero embryonic development; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human HES3 (hes family bHLH transcription factor 3); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; hexaconazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHb43; hairy and enhancer of split 3; hairy and enhancer of split 3 (Drosophila); Hes-3; MGC144657; transcription factor HES-3
Homo sapiens (human) : HES3 (hes family bHLH transcription factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hes3 (hes family bHLH transcription factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hes3 (hes family bHLH transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HES3 (hes family bHLH transcription factor 3)
Canis lupus familiaris (dog) : HES3 (hes family bHLH transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes3 (hes family bHLH transcription factor 3)
Sus scrofa (pig) : HES3 (hes family bHLH transcription factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384152,285,250 - 152,291,911 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374151,660,081 - 151,665,771 (-)NCBIGRCm37mm9NCBIm37
MGSCv364151,129,772 - 151,135,462 (-)NCBImm8
Celera4154,572,853 - 154,579,001 (-)NCBICelera
Cytogenetic Map4 E2NCBI
cM Map483.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hes3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733887
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.