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Gene: Gsk3b (glycogen synthase kinase 3 beta) Mus musculus
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Symbol: Gsk3b
Name: glycogen synthase kinase 3 beta
Description: Exhibits several functions, including beta-catenin binding activity; dynein complex binding activity; and protein kinase activity. Involved in several processes, including cell surface receptor signaling pathway; generation of neurons; and positive regulation of cellular metabolic process. Localizes to several cellular components, including the Wnt signalosome; beta-catenin destruction complex; and dendritic shaft. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; and schizophrenia. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human GSK3B (glycogen synthase kinase 3 beta); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; glycogen biosynthetic pathway; Hedgehog signaling pathway; INTERACTS WITH (R)-lipoic acid; 1-chloro-2,4-dinitrobenzene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 7330414F15Rik; 8430431H08Rik; C86142; glycogen synthase kinase-3 beta; GSK-3; GSK-3 beta; GSK-3beta; GSK3; serine/threonine-protein kinase GSK3B
Orthologs:
Homo sapiens (human) : GSK3B (glycogen synthase kinase 3 beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gsk3b (glycogen synthase kinase 3 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsk3b (glycogen synthase kinase 3 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GSK3B (glycogen synthase kinase 3 beta)
Canis lupus familiaris (dog) : GSK3B (glycogen synthase kinase 3 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsk3b (glycogen synthase kinase 3 beta)
Sus scrofa (pig) : GSK3B (glycogen synthase kinase 3 beta)
Chlorocebus sabaeus (African green monkey) : GSK3B (glycogen synthase kinase 3 beta)
Heterocephalus glaber (naked mole-rat) : Gsk3b (glycogen synthase kinase 3 beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1638,089,001 - 38,246,084 (+)EnsemblGRCm38mm10GRCm38
GRCm381638,089,001 - 38,246,084 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371638,089,087 - 38,246,165 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,008,240 - 38,165,318 (+)NCBImm8
Celera1638,497,488 - 38,655,086 (+)NCBICelera
Cytogenetic Map16B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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Sequence

Nucleotide Sequences
Protein Sequences