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Gene: HSPD1 (heat shock protein family D (Hsp60) member 1) Homo sapiens
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Symbol: HSPD1
Name: heat shock protein family D (Hsp60) member 1
Description: Exhibits several functions, including apolipoprotein A-I binding activity; chaperone binding activity; and high-density lipoprotein particle binding activity. Involved in several processes, including B cell mediated immunity; positive regulation of cytokine production; and positive regulation of leukocyte activation. Localizes to several cellular components, including the cytoplasmic vesicle; extracellular exosome; and lipopolysaccharide receptor complex. Implicated in artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Biomarker of several diseases, including Down syndrome; aphthous stomatitis; cystic fibrosis; rheumatoid arthritis (multiple); and systemic lupus erythematosus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; chaperonin 60; CPN60; GROEL; heat shock 60kDa protein 1 (chaperonin); heat shock protein 60 (liver); heat shock protein 65; HLD4; HSP-60; HSP60; HSP65; HuCHA60; mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; spastic paraplegia 13 (autosomal dominant); SPG13
Orthologs:
Mus musculus (house mouse) : Hspd1 (heat shock protein 1 (chaperonin))  MGI  Alliance
Rattus norvegicus (Norway rat) : Hspd1 (heat shock protein family D (Hsp60) member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspd1 (heat shock protein family D (Hsp60) member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Canis lupus familiaris (dog) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspd1 (heat shock protein family D (Hsp60) member 1)
Sus scrofa (pig) : HSPD1 (heat shock protein family D (Hsp60) member 1)
more info ...
Related Pseudogenes: HSPD1P1   HSPD1P10   HSPD1P11   HSPD1P12   HSPD1P13   HSPD1P14   HSPD1P15   HSPD1P16   HSPD1P17   HSPD1P18   HSPD1P19   HSPD1P2   HSPD1P20   HSPD1P21   HSPD1P22   HSPD1P3   HSPD1P4   HSPD1P5   HSPD1P6   HSPD1P7   HSPD1P8   HSPD1P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382197,486,584 - 197,500,274 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372198,351,308 - 198,364,998 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362198,059,553 - 198,073,243 (-)NCBINCBI36hg18NCBI36
Build 342198,176,815 - 198,190,504NCBI
Celera2192,107,181 - 192,120,871 (-)NCBI
Cytogenetic Map2q33.1NCBI
HuRef2190,203,711 - 190,217,402 (-)NCBIHuRef
CHM1_12198,357,144 - 198,370,838 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on HSPD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733895
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.