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Gene: Prdx5 (peroxiredoxin 5) Mus musculus
Symbol: Prdx5
Name: peroxiredoxin 5
Description: Predicted to have several functions, including RNA polymerase III regulatory region DNA binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and peroxiredoxin activity. Predicted to be involved in several processes, including NADPH oxidation; cell redox homeostasis; and regulation of apoptotic process. Localizes to the mitochondrion. Is expressed in several structures, including central nervous system; genitourinary system; retina; salivary gland; and spleen. Orthologous to human PRDX5 (peroxiredoxin 5).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antioxidant enzyme B166; AOEB166; AOPP; liver tissue 2D-page spot 2D-0014IV; peroxiredoxin 6; peroxiredoxin V; peroxiredoxin-5, mitochondrial; peroxisomal antioxidant enzyme; peroxisomal membrane protein 20; PLP; Pmp20; Prdx6; prx-V; PrxV; thioredoxin peroxidase PMP20; thioredoxin reductase
Homo sapiens (human) : PRDX5 (peroxiredoxin 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prdx5 (peroxiredoxin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx5 (peroxiredoxin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX5 (peroxiredoxin 5)
Canis lupus familiaris (dog) : PRDX5 (peroxiredoxin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx5 (peroxiredoxin 5)
Sus scrofa (pig) : PRDX5 (peroxiredoxin 5)
Chlorocebus sabaeus (African green monkey) : PRDX5 (peroxiredoxin 5)
Heterocephalus glaber (naked mole-rat) : Prdx5 (peroxiredoxin 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl196,906,697 - 6,910,106 (-)Ensembl
GRCm38196,906,697 - 6,910,106 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,981,309 - 6,984,135 (-)NCBIGRCm37mm9NCBIm37
MGSCv36196,973,863 - 6,976,689 (-)NCBImm8
Celera196,683,601 - 6,686,426 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map195.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prdx5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733919
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.