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Gene: Tle3 (transducin-like enhancer of split 3) Mus musculus
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Symbol: Tle3
Name: transducin-like enhancer of split 3
Description: Predicted to have repressing transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of cold-induced thermogenesis. Predicted to localize to the beta-catenin-TCF complex and nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610103N05Rik; ESG; grg-3; Grg3a; Grg3b; mKIAA1547; transducin-like enhancer of split 3, homolog of Drosophila E(spl); transducin-like enhancer protein 3
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38961,372,326 - 61,418,497 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37961,220,173 - 61,266,304 (+)NCBIGRCm37mm9NCBIm37
MGSCv36961,171,678 - 61,214,990 (+)NCBImm8
Celera958,595,799 - 58,641,869 (+)NCBICelera
Cytogenetic Map9 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tle3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733929
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.