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Gene: Hcn1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1) Mus musculus
Symbol: Hcn1
Name: hyperpolarization activated cyclic nucleotide gated potassium channel 1
Description: Exhibits cAMP binding activity; cation channel activity; and identical protein binding activity. Involved in several processes, including apical protein localization; cellular response to cAMP; and retinal cone cell development. Localizes to axon; dendrite; and integral component of plasma membrane. Is expressed in brain; heart; and heart ventricle. Used to study sick sinus syndrome. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 24 and generalized epilepsy with febrile seizures plus 10. Orthologous to human HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1); INTERACTS WITH 4,4'-sulfonyldiphenol; folic acid; gamma-aminobutyric acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bcng; BCNG-1; Bcng1; brain cyclic nucleotide-gated channel 1; C630013B14Rik; HAC; HAC-2; HAC2; hyperpolarization-activated cation channel 2; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1; RIKEN cDNA C630013B14 gene
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl13117,602,320 - 117,987,418 (+)EnsemblGRCm38mm10GRCm38
GRCm3813117,602,320 - 117,981,028 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3713118,391,127 - 118,769,835 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613118,721,981 - 119,096,083 (+)NCBImm8
Celera13122,021,998 - 122,417,756 (+)NCBICelera
Cytogenetic Map13D2.3NCBI
cM Map1366.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hcn1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733931
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.