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Gene: CLASP2 (cytoplasmic linker associated protein 2) Homo sapiens
Symbol: CLASP2
Name: cytoplasmic linker associated protein 2
CRRD ID: 733933
Description: Exhibits cytoskeletal protein binding activity; dystroglycan binding activity; and protein tyrosine kinase binding activity. Involved in several processes, including microtubule cytoskeleton organization; positive regulation of extracellular matrix organization; and regulation of supramolecular fiber organization. Localizes to several cellular components, including basal cortex; cortical microtubule plus-end; and ruffle membrane. Colocalizes with focal adhesion; kinetochore; and mitotic spindle; INTERACTS WITH (-)-demecolcine; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CLIP-associating protein 2; CLIP-associating protein CLASP2; cytoplasmic linker-associated protein 2; hOrbit2; multiple asters (Mast)-like homolog 2; protein Orbit homolog 2
Mus musculus (house mouse) : Clasp2 (CLIP associating protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clasp2 (cytoplasmic linker associated protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clasp2 (cytoplasmic linker associated protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLASP2 (cytoplasmic linker associated protein 2)
Canis lupus familiaris (dog) : CLASP2 (cytoplasmic linker associated protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clasp2 (cytoplasmic linker associated protein 2)
Sus scrofa (pig) : CLASP2 (cytoplasmic linker associated protein 2)
Chlorocebus sabaeus (African green monkey) : CLASP2 (cytoplasmic linker associated protein 2)
Heterocephalus glaber (naked mole-rat) : Clasp2 (cytoplasmic linker associated protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl333,496,245 - 33,718,356 (-)EnsemblGRCh38hg38GRCh38
GRCh38333,496,245 - 33,718,356 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37333,537,737 - 33,759,705 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,512,741 - 33,734,852 (-)NCBINCBI36hg18NCBI36
Build 34333,512,741 - 33,734,852NCBI
Celera333,481,199 - 33,702,919 (-)NCBI
Cytogenetic Map3p22.3NCBI
HuRef333,478,162 - 33,700,169 (-)NCBIHuRef
CHM1_1333,487,717 - 33,709,704 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CLASP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733933
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.