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Gene: ABCC8 (ATP binding cassette subfamily C member 8) Homo sapiens
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Symbol: ABCC8
Name: ATP binding cassette subfamily C member 8
Description: Exhibits ATPase activity; ion channel binding activity; and potassium channel activity. Predicted to be involved in inorganic cation transmembrane transport. Localizes to the inward rectifying potassium channel. Implicated in familial hyperinsulinemic hypoglycemia 1; hyperinsulinism; hypertension; permanent neonatal diabetes mellitus; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABC36; ATP-binding cassette sub-family C member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; atp-binding cassette, subfamily c (cftr/mrp), member 8; HHF1; HI; HRINS; MRP8; PHHI; sulfonylurea receptor (hyperinsulinemia); sulfonylurea receptor 1; SUR; SUR1; SUR1delta2; TNDM2
Orthologs:
Mus musculus (house mouse) : Abcc8 (ATP-binding cassette, sub-family C (CFTR/MRP), member 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcc8 (ATP binding cassette subfamily C member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc8 (ATP binding cassette subfamily C member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC8 (ATP binding cassette subfamily C member 8)
Canis lupus familiaris (dog) : ABCC8 (ATP binding cassette subfamily C member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc8 (ATP binding cassette subfamily C member 8)
Sus scrofa (pig) : ABCC8 (ATP binding cassette subfamily C member 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381117,392,498 - 17,476,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,414,432 - 17,498,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,371,008 - 17,455,025 (-)NCBINCBI36hg18NCBI36
Build 341117,371,008 - 17,455,025NCBI
Celera1117,544,259 - 17,628,301 (-)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1117,098,250 - 17,182,251 (-)NCBIHuRef
CHM1_11117,414,230 - 17,498,217 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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