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Gene: Cul5 (cullin 5) Mus musculus
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Symbol: Cul5
Name: cullin 5
Description: Exhibits protein heterodimerization activity. Involved in cerebral cortex radially oriented cell migration; protein ubiquitination; and radial glia guided migration of Purkinje cell. Predicted to localize to several cellular components, including the cullin-RING ubiquitin ligase complex; nucleus; and site of DNA damage. Is expressed in several structures, including 1st branchial arch mandibular component; central nervous system; eye; genitourinary system; and limb bud. Orthologous to human CUL5 (cullin 5); PARTICIPATES IN neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; ubiquitin/proteasome degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; CUL-5; cullin-5; VACM-1; VACM1; vasopressin-activated calcium-mobilizing receptor protein
Orthologs:
Homo sapiens (human) : CUL5 (cullin 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cul5 (cullin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul5 (cullin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL5 (cullin 5)
Canis lupus familiaris (dog) : CUL5 (cullin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul5 (cullin 5)
Sus scrofa (pig) : CUL5 (cullin 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38953,614,581 - 53,667,507 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37953,422,687 - 53,475,612 (-)NCBIGRCm37mm9NCBIm37
MGSCv36953,379,265 - 53,429,872 (-)NCBImm8
Celera950,874,391 - 50,927,173 (-)NCBICelera
Cytogenetic Map9 A5.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cul5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733948
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.