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Gene: Pnpo (pyridoxine 5'-phosphate oxidase) Mus musculus
Symbol: Pnpo
Name: pyridoxine 5'-phosphate oxidase
CRRD ID: 733973
Description: Predicted to have coenzyme binding activity; protein homodimerization activity; and pyridoxamine-phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase); PARTICIPATES IN hypophosphatasia pathway; vitamin B6 metabolic pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI415282; pyridoxamine-phosphate oxidase; pyridoxine-5'-phosphate oxidase
Homo sapiens (human) : PNPO (pyridoxamine 5'-phosphate oxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pnpo (pyridoxamine 5'-phosphate oxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnpo (pyridoxamine 5'-phosphate oxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : PNPO (pyridoxamine 5'-phosphate oxidase)
Canis lupus familiaris (dog) : PNPO (pyridoxamine 5'-phosphate oxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnpo (pyridoxamine 5'-phosphate oxidase)
Sus scrofa (pig) : PNPO (pyridoxamine 5'-phosphate oxidase)
Chlorocebus sabaeus (African green monkey) : PNPO (pyridoxamine 5'-phosphate oxidase)
Heterocephalus glaber (naked mole-rat) : Pnpo (pyridoxamine 5'-phosphate oxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1196,937,825 - 96,943,986 (-)EnsemblGRCm38mm10GRCm38
GRCm381196,937,816 - 96,944,019 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371196,799,130 - 96,805,333 (-)NCBIGRCm37mm9NCBIm37
MGSCv361196,753,917 - 96,770,309 (-)NCBImm8
Celera11106,585,705 - 106,591,891 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pnpo
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733973
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.