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Gene: Pnpo (pyridoxine 5'-phosphate oxidase) Mus musculus
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Symbol: Pnpo
Name: pyridoxine 5'-phosphate oxidase
CRRD ID: 733973
Description: Predicted to have coenzyme binding activity; protein homodimerization activity; and pyridoxamine-phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Orthologous to human PNPO (pyridoxamine 5'-phosphate oxidase); PARTICIPATES IN hypophosphatasia pathway; vitamin B6 metabolic pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI415282; pyridoxamine-phosphate oxidase; pyridoxine-5'-phosphate oxidase
Orthologs:
Homo sapiens (human) : PNPO (pyridoxamine 5'-phosphate oxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pnpo (pyridoxamine 5'-phosphate oxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnpo (pyridoxamine 5'-phosphate oxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : PNPO (pyridoxamine 5'-phosphate oxidase)
Canis lupus familiaris (dog) : PNPO (pyridoxamine 5'-phosphate oxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnpo (pyridoxamine 5'-phosphate oxidase)
Sus scrofa (pig) : PNPO (pyridoxamine 5'-phosphate oxidase)
Chlorocebus sabaeus (African green monkey) : PNPO (pyridoxamine 5'-phosphate oxidase)
Heterocephalus glaber (naked mole-rat) : Pnpo (pyridoxamine 5'-phosphate oxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1196,937,825 - 96,943,986 (-)EnsemblGRCm38mm10GRCm38
GRCm381196,937,816 - 96,944,019 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371196,799,130 - 96,805,333 (-)NCBIGRCm37mm9NCBIm37
MGSCv361196,753,917 - 96,770,309 (-)NCBImm8
Celera11106,585,705 - 106,591,891 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pnpo
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733973
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.