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Gene: SLC18A2 (solute carrier family 18 member A2) Homo sapiens
Symbol: SLC18A2
Name: solute carrier family 18 member A2
Description: Predicted to have serotonin:sodium symporter activity. Predicted to be involved in aminergic neurotransmitter loading into synaptic vesicle. Localizes to centrosome and intracellular membrane-bounded organelle. Implicated in Parkinson's disease. Biomarker of Parkinson's disease and type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; monoamine transporter; PKDYS2; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; solute carrier family 18 member 2; solute carrier family 18, member 2; SVAT; SVMT; synaptic vesicle amine transporter, brain; synaptic vesicle monoamine transporter, brain; synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; vesicular amine transporter 2; VMAT2
Mus musculus (house mouse) : Slc18a2 (solute carrier family 18 (vesicular monoamine), member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc18a2 (solute carrier family 18 member A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc18a2 (solute carrier family 18 member A2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A2 (solute carrier family 18 member A2)
Canis lupus familiaris (dog) : SLC18A2 (solute carrier family 18 member A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc18a2 (solute carrier family 18 member A2)
Sus scrofa (pig) : SLC18A2 (solute carrier family 18 member A2)
Chlorocebus sabaeus (African green monkey) : SLC18A2 (solute carrier family 18 member A2)
Heterocephalus glaber (naked mole-rat) : Slc18a2 (solute carrier family 18 member A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10117,241,093 - 117,279,430 (+)EnsemblGRCh38hg38GRCh38
GRCh3810117,241,114 - 117,279,430 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710119,000,584 - 119,038,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,990,706 - 119,027,085 (+)NCBINCBI36hg18NCBI36
Build 3410118,991,172 - 119,027,085NCBI
Celera10112,730,694 - 112,769,064 (+)NCBI
Cytogenetic Map10q25.3NCBI
HuRef10112,628,076 - 112,666,635 (+)NCBIHuRef
CHM1_110119,284,792 - 119,323,133 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC18A2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734009
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.