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Gene: DDB1 (damage specific DNA binding protein 1) Homo sapiens
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Symbol: DDB1
Name: damage specific DNA binding protein 1
CRRD ID: 734016
Description: Exhibits WD40-repeat domain binding activity; cullin family protein binding activity; and protein-macromolecule adaptor activity. Contributes to damaged DNA binding activity. Involved in several processes, including UV-damage excision repair; cellular protein metabolic process; and positive regulation of viral process. Localizes to Cul4-RING E3 ubiquitin ligase complex; cytoplasm; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: damage-specific dna binding protein 1; damage-specific DNA binding protein 1, 127kDa; damage-specific DNA-binding protein 1; DDB p127 subunit; DDBA; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; XAP-1; XAP1; xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor
Orthologs:
Mus musculus (house mouse) : Ddb1 (damage specific DNA binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ddb1 (damage-specific DNA binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddb1 (damage specific DNA binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DDB1 (damage specific DNA binding protein 1)
Canis lupus familiaris (dog) : DDB1 (damage specific DNA binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddb1 (damage specific DNA binding protein 1)
Sus scrofa (pig) : DDB1 (damage specific DNA binding protein 1)
Chlorocebus sabaeus (African green monkey) : DDB1 (damage specific DNA binding protein 1)
Heterocephalus glaber (naked mole-rat) : Ddb1 (damage specific DNA binding protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1161,299,451 - 61,342,596 (-)EnsemblGRCh38hg38GRCh38
GRCh381161,299,451 - 61,333,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,066,919 - 61,100,691 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,823,495 - 60,857,242 (-)NCBINCBI36hg18NCBI36
Build 341160,823,499 - 60,857,125NCBI
Cytogenetic Map11q12.2NCBI
HuRef1157,394,763 - 57,428,510 (-)NCBIHuRef
CHM1_11160,949,958 - 60,983,704 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DDB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734016
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.