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Gene: SRSF5 (serine and arginine rich splicing factor 5) Homo sapiens
Symbol: SRSF5
Name: serine and arginine rich splicing factor 5
Description: Exhibits RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome; and response to wounding. Localizes to cytosol; nucleolus; and nucleoplasm. Biomarker of breast cancer; clear cell renal cell carcinoma; and colon adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: delayed-early protein HRS; HRS; pre-mRNA-splicing factor SRP40; serine/arginine-rich splicing factor 5; SFRS5; splicing factor, arginine/serine-rich 5; SR splicing factor 5; SRP40
Mus musculus (house mouse) : Srsf5 (serine and arginine-rich splicing factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srsf5 (serine and arginine rich splicing factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf5 (serine and arginine rich splicing factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF5 (serine and arginine rich splicing factor 5)
Canis lupus familiaris (dog) : SRSF5 (serine and arginine rich splicing factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf5 (serine and arginine rich splicing factor 5)
Sus scrofa (pig) : SRSF5 (serine and arginine rich splicing factor 5)
Chlorocebus sabaeus (African green monkey) : SRSF5 (serine and arginine rich splicing factor 5)
Heterocephalus glaber (naked mole-rat) : Srsf5 (serine and arginine rich splicing factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1469,726,900 - 69,772,005 (+)EnsemblGRCh38hg38GRCh38
GRCh381469,767,112 - 69,772,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371470,233,812 - 70,238,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361469,303,582 - 69,308,475 (+)NCBINCBI36hg18NCBI36
Build 341469,303,562 - 69,308,474NCBI
Celera1450,297,941 - 50,302,834 (+)NCBI
Cytogenetic Map14q24.1NCBI
HuRef1450,402,386 - 50,407,279 (+)NCBIHuRef
CHM1_11470,171,946 - 70,176,864 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SRSF5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734021
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.