Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: FOLH1 (folate hydrolase 1) Homo sapiens
Symbol: FOLH1
Name: folate hydrolase 1
Description: Exhibits Ac-Asp-Glu binding activity; metallocarboxypeptidase activity; and tetrahydrofolyl-poly(glutamate) polymer binding activity. Involved in C-terminal protein deglutamylation and proteolysis. Localizes to the cell surface and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cell growth-inhibiting gene 27 protein; cell growth-inhibiting protein 27; FGCP; folate hydrolase; folate hydrolase (prostate-specific membrane antigen) 1; FOLH; folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase 2; glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; NAALAD1; NAALAdase; NAALADase I; prostate specific membrane antigen variant F; prostate-specific membrane antigen; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase
Mus musculus (house mouse) : Folh1 (folate hydrolase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Folh1 (folate hydrolase 1)  Alliance
Canis lupus familiaris (dog) : FOLH1 (folate hydrolase (prostate-specific membrane antigen) 1)
Sus scrofa (pig) : FOLH1B (folate hydrolase 1B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1149,145,092 - 49,208,638 (-)Ensembl
GRCh381149,145,092 - 49,208,642 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371149,168,187 - 49,230,222 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,124,763 - 49,186,798 (-)NCBINCBI36hg18NCBI36
Build 341149,124,763 - 49,186,798NCBI
Celera1149,319,516 - 49,381,546 (-)NCBI
Cytogenetic Map11p11.12NCBI
HuRef1148,886,315 - 48,948,370 (-)NCBIHuRef
CHM1_11149,166,592 - 49,228,610 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FOLH1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734060
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.