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Gene: Mmp14 (matrix metallopeptidase 14 (membrane-inserted)) Mus musculus
Symbol: Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Description: Exhibits metalloendopeptidase activity. Involved in several processes, including chondrocyte proliferation; positive regulation of cell differentiation; and skeletal system morphogenesis. Predicted to localize to several cellular components, including the extracellular space; intermediate filament cytoskeleton; and macropinosome. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in myocardial infarction. Is expressed in several structures, including 1st branchial arch; head mesenchyme; midbrain mantle layer; reproductive system; and stylopod. Orthologous to human MMP14 (matrix metallopeptidase 14).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI325305; matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase-14; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-14; MMP-X1; MT-MMP 1; MT-MMP-1; MT1-MMP; MT1MMP; MTMMP1; sabe; type 1 matrix metalloprotease 14
Homo sapiens (human) : MMP14 (matrix metallopeptidase 14)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mmp14 (matrix metallopeptidase 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp14 (matrix metallopeptidase 14)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP14 (matrix metallopeptidase 14)
Canis lupus familiaris (dog) : MMP14 (matrix metallopeptidase 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp14 (matrix metallopeptidase 14)
Sus scrofa (pig) : MMP14 (matrix metallopeptidase 14)
Chlorocebus sabaeus (green monkey) : MMP14 (matrix metallopeptidase 14)
Heterocephalus glaber (naked mole-rat) : Mmp14 (matrix metallopeptidase 14)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1454,431,612 - 54,445,364 (+)Ensembl
GRCm381454,431,598 - 54,442,456 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371455,050,441 - 55,060,095 (+)NCBIGRCm37mm9NCBIm37
MGSCv361453,385,824 - 53,395,458 (+)NCBImm8
Celera1452,223,646 - 52,233,174 (+)NCBICelera
Cytogenetic Map14 C2NCBI
cM Map1427.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mmp14
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734119
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.