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Gene: Mmp14 (matrix metallopeptidase 14 (membrane-inserted)) Mus musculus
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Symbol: Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Description: Exhibits metalloendopeptidase activity. Involved in several processes, including chondrocyte proliferation; positive regulation of cell differentiation; and skeletal system morphogenesis. Predicted to localize to several cellular components, including the extracellular space; intermediate filament cytoskeleton; and macropinosome. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in myocardial infarction. Is expressed in several structures, including 1st branchial arch; head mesenchyme; midbrain mantle layer; reproductive system; and stylopod. Orthologous to human MMP14 (matrix metallopeptidase 14).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI325305; matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase-14; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-14; MMP-X1; MT-MMP 1; MT-MMP-1; MT1-MMP; MT1MMP; MTMMP1; sabe; type 1 matrix metalloprotease 14
Orthologs:
Homo sapiens (human) : MMP14 (matrix metallopeptidase 14)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mmp14 (matrix metallopeptidase 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp14 (matrix metallopeptidase 14)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP14 (matrix metallopeptidase 14)
Canis lupus familiaris (dog) : MMP14 (matrix metallopeptidase 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp14 (matrix metallopeptidase 14)
Sus scrofa (pig) : MMP14 (matrix metallopeptidase 14)
Chlorocebus sabaeus (green monkey) : MMP14 (matrix metallopeptidase 14)
Heterocephalus glaber (naked mole-rat) : Mmp14 (matrix metallopeptidase 14)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1454,431,612 - 54,445,364 (+)Ensembl
GRCm381454,431,598 - 54,442,456 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371455,050,441 - 55,060,095 (+)NCBIGRCm37mm9NCBIm37
MGSCv361453,385,824 - 53,395,458 (+)NCBImm8
Celera1452,223,646 - 52,233,174 (+)NCBICelera
Cytogenetic Map14 C2NCBI
cM Map1427.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mmp14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734119
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.