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Gene: SYTL4 (synaptotagmin like 4) Homo sapiens
Symbol: SYTL4
Name: synaptotagmin like 4
Description: This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp451P0116; exophilin-2; FLJ40960; granuphilin-a; SLP4; synaptotagmin-like protein 4
Mus musculus (house mouse) : Sytl4 (synaptotagmin-like 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sytl4 (synaptotagmin-like 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sytl4 (synaptotagmin like 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SYTL4 (synaptotagmin like 4)
Canis lupus familiaris (dog) : SYTL4 (synaptotagmin like 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sytl4 (synaptotagmin like 4)
Sus scrofa (pig) : SYTL4 (synaptotagmin like 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X100,671,964 - 100,732,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X99,929,488 - 99,987,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,816,144 - 99,873,154 (-)NCBINCBI36hg18NCBI36
Build 34X99,735,633 - 99,792,643NCBI
CeleraX100,448,228 - 100,505,895 (-)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX89,729,520 - 89,785,468 (-)NCBIHuRef
CHM1_1X99,822,386 - 99,880,040 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SYTL4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734138
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.