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Gene: ELOB (elongin B) Homo sapiens
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Symbol: ELOB
Name: elongin B
Description: Exhibits ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including cellular protein modification process; regulation of transcription from RNA polymerase II promoter in response to hypoxia; and transcription elongation from RNA polymerase II promoter. Localizes to the Cul2-RING ubiquitin ligase complex and Cul5-RING ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: elongin 18 kDa subunit; elongin, 18-kD subunit; elongin-B; RNA polymerase II transcription factor SIII p18 subunit; RNA polymerase II transcription factor SIII subunit B; SIII; SIII p18; TCEB2; transcription elongation factor b (siii) polypeptide 2 (18kd, elongin b); transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); transcription elongation factor B polypeptide 2; transcription elongation factor B subunit 2
Orthologs:
Mus musculus (house mouse) : Elob (elongin B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Elob (elongin B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elob (elongin B)
Pan paniscus (bonobo/pygmy chimpanzee) : ELOB (elongin B)
Canis lupus familiaris (dog) : ELOB (elongin B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elob (elongin B)
Sus scrofa (pig) : ELOB (elongin B)
more info ...
Related Pseudogenes: ELOBP1   ELOBP2   ELOBP3   ELOBP4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,771,414 - 2,777,280 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37162,821,415 - 2,827,297 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,761,416 - 2,767,298 (-)NCBINCBI36hg18NCBI36
Build 34162,761,416 - 2,767,298NCBI
Celera163,020,982 - 3,026,862 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef162,788,655 - 2,794,449 (-)NCBIHuRef
CHM1_1162,821,459 - 2,827,327 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ELOB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734149
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.