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Gene: Snap25 (synaptosomal-associated protein 25) Mus musculus
Symbol: Snap25
Name: synaptosomal-associated protein 25
Description: Exhibits syntaxin-1 binding activity. Involved in several processes, including neurotransmitter receptor transport; regulation of synaptic plasticity; and synaptic vesicle exocytosis. Localizes to several cellular components, including the extrinsic component of cytoplasmic side of plasma membrane; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; and trans-Golgi network. Predicted to colocalize with the BLOC-1 complex and vesicle. Used to study attention deficit hyperactivity disorder; obesity; schizophrenia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Is expressed in adrenal gland; jaw; nervous system; and sensory organ. Orthologous to human SNAP25 (synaptosome associated protein 25); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 2,2,2-tetramine; bisphenol A; Botulinum toxin type A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bdr; blind drunk; GENA 70; GENA70; SNAP-25; sp; SUP; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein, 25 kDa
Homo sapiens (human) : SNAP25 (synaptosome associated protein 25)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Snap25 (synaptosome associated protein 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snap25 (synaptosome associated protein 25)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAP25 (synaptosome associated protein 25)
Canis lupus familiaris (dog) : SNAP25 (synaptosome associated protein 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snap25 (synaptosome associated protein 25)
Sus scrofa (pig) : SNAP25 (synaptosome associated protein 25)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382136,713,439 - 136,782,428 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372136,539,186 - 136,608,164 (+)NCBIGRCm37mm9NCBIm37
MGSCv362136,404,944 - 136,473,857 (+)NCBImm8
Celera2137,909,643 - 137,978,489 (+)NCBICelera
Cytogenetic Map2 F3NCBI
cM Map267.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Snap25
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734152
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.