Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Snap25 (synaptosomal-associated protein 25) Mus musculus
Analyze
Symbol: Snap25
Name: synaptosomal-associated protein 25
Description: Exhibits syntaxin-1 binding activity. Involved in several processes, including neurotransmitter receptor transport; regulation of synaptic plasticity; and synaptic vesicle exocytosis. Localizes to several cellular components, including the extrinsic component of cytoplasmic side of plasma membrane; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; and trans-Golgi network. Predicted to colocalize with the BLOC-1 complex and vesicle. Used to study attention deficit hyperactivity disorder; obesity; schizophrenia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Is expressed in adrenal gland; jaw; nervous system; and sensory organ. Orthologous to human SNAP25 (synaptosome associated protein 25); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 2,2,2-tetramine; bisphenol A; Botulinum toxin type A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bdr; blind drunk; GENA 70; GENA70; SNAP-25; sp; SUP; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein, 25 kDa
Orthologs:
Homo sapiens (human) : SNAP25 (synaptosome associated protein 25)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Snap25 (synaptosome associated protein 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snap25 (synaptosome associated protein 25)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAP25 (synaptosome associated protein 25)
Canis lupus familiaris (dog) : SNAP25 (synaptosome associated protein 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snap25 (synaptosome associated protein 25)
Sus scrofa (pig) : SNAP25 (synaptosome associated protein 25)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382136,713,439 - 136,782,428 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372136,539,186 - 136,608,164 (+)NCBIGRCm37mm9NCBIm37
MGSCv362136,404,944 - 136,473,857 (+)NCBImm8
Celera2137,909,643 - 137,978,489 (+)NCBICelera
Cytogenetic Map2 F3NCBI
cM Map267.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Snap25
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734152
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.