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Gene: ARF6 (ADP ribosylation factor 6) Homo sapiens
Symbol: ARF6
Name: ADP ribosylation factor 6
Description: Exhibits thioesterase binding activity. Involved in several processes, including positive regulation of protein homodimerization activity; regulation of Rac protein signal transduction; and ruffle assembly. Localizes to several cellular components, including the Flemming body; cytoplasmic vesicle; and filopodium membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosylation factor 6; DKFZp564M0264
Mus musculus (house mouse) : Arf6 (ADP-ribosylation factor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arf6 (ADP-ribosylation factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arf6 (ADP ribosylation factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ARF6 (ADP ribosylation factor 6)
Canis lupus familiaris (dog) : ARF6 (ADP ribosylation factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arf6 (ADP ribosylation factor 6)
Sus scrofa (pig) : ARF6 (ADP ribosylation factor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1449,893,082 - 49,897,054 (+)Ensembl
GRCh381449,893,082 - 49,897,054 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371450,359,736 - 50,363,772 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361449,429,486 - 49,433,522 (+)NCBINCBI36hg18NCBI36
Build 341449,429,588 - 49,431,484NCBI
Celera1430,226,871 - 30,230,907 (+)NCBI
Cytogenetic Map14q21.3NCBI
HuRef1430,484,292 - 30,488,326 (+)NCBIHuRef
CHM1_11450,297,978 - 50,302,011 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARF6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734181
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.