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Gene: Mif (macrophage migration inhibitory factor (glycosylation-inhibiting factor)) Mus musculus
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Symbol: Mif
Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
CRRD ID: 734204
Description: Exhibits cytokine activity; phenylpyruvate tautomerase activity; and protease binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of icosanoid secretion; and positive regulation of protein phosphorylation. Localizes to extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in allergic hypersensitivity disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Orthologous to human MIF (macrophage migration inhibitory factor); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH 1-fluoro-2,4-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: delayed early response protein 6; DER6; GIF; Gl; Glif; glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; MGC107654; phenylpyruvate tautomerase
Orthologs:
Homo sapiens (human) : MIF (macrophage migration inhibitory factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mif (macrophage migration inhibitory factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mif (macrophage migration inhibitory factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MIF (macrophage migration inhibitory factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mif (macrophage migration inhibitory factor)
Sus scrofa (pig) : MIF (macrophage migration inhibitory factor)
Chlorocebus sabaeus (African green monkey) : MIF (macrophage migration inhibitory factor)
Heterocephalus glaber (naked mole-rat) : Mif (macrophage migration inhibitory factor)
more info ...
Related Pseudogenes: Gm5228   Gm6990   Mif-ps   Mif-ps1   Mif-ps10   Mif-ps11   Mif-ps12   Mif-ps13   Mif-ps2   Mif-ps3   Mif-ps5   Mif-ps6   Mif-ps7  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1075,859,353 - 75,860,240 (-)EnsemblGRCm38mm10GRCm38
GRCm381075,859,353 - 75,860,277 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,322,098 - 75,322,995 (-)NCBIGRCm37mm9NCBIm37
MGSCv361075,303,069 - 75,303,966 (-)NCBImm8
Celera1076,904,043 - 76,904,940 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Mif
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734204
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.