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Gene: ARL3 (ADP ribosylation factor like GTPase 3) Homo sapiens
Symbol: ARL3
Name: ADP ribosylation factor like GTPase 3
Description: Exhibits GDP binding activity; GTP binding activity; and microtubule binding activity. Involved in several processes, including post-Golgi vesicle-mediated transport; protein localization to cilium; and small GTPase mediated signal transduction. Localizes to several cellular components, including microtubule cytoskeleton; midbody; and photoreceptor connecting cilium. Implicated in Joubert syndrome and retinitis pigmentosa.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosylation factor like GTPase 3; ADP-ribosylation factor-like 3; ADP-ribosylation factor-like protein 3; adp-ribosylation-like 3; ARF-like 3; ARFL3; JBTS35; RP83
Mus musculus (house mouse) : Arl3 (ADP-ribosylation factor-like 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arl3 (ADP ribosylation factor like GTPase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arl3 (ADP ribosylation factor like GTPase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ARL3 (ADP ribosylation factor like GTPase 3)
Canis lupus familiaris (dog) : ARL3 (ADP ribosylation factor like GTPase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arl3 (ADP ribosylation factor like GTPase 3)
Sus scrofa (pig) : ARL3 (ADP ribosylation factor like GTPase 3)
Heterocephalus glaber (naked mole-rat) : Arl3 (ADP ribosylation factor like GTPase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10102,673,731 - 102,714,397 (-)EnsemblGRCh38hg38GRCh38
GRCh3810102,673,731 - 102,714,397 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710104,433,484 - 104,474,190 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610104,423,478 - 104,464,180 (-)NCBINCBI36hg18NCBI36
Build 3410104,423,479 - 104,464,180NCBI
Celera1098,174,570 - 98,215,252 (-)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1098,068,111 - 98,108,671 (-)NCBIHuRef
CHM1_110104,717,244 - 104,757,972 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARL3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734227
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.