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Gene: Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a) Mus musculus
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Symbol: Tnfrsf1a
Name: tumor necrosis factor receptor superfamily, member 1a
Description: Exhibits tumor necrosis factor-activated receptor activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of extracellular matrix constituent secretion; and semi-lunar valve development. Localizes to the cell surface and membrane raft. Used to study autosomal dominant familial periodic fever. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; Legionnaires' disease; acne; allergic bronchopulmonary aspergillosis; and autosomal dominant familial periodic fever. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; lung; and reproductive system. Orthologous to human TNFRSF1A (TNF receptor superfamily member 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD120a; FPF; p55; p55-R; p60; TNF receptor alpha chain; TNF-alpha-R1; TNF-alphaR1; TNF-R; TNF-R-I; TNF-R1; TNF-R55; TNF-RI; TNFalpha-R1; TNFAR; Tnfr-2; TNFR-I; Tnfr1; TNFR60; TNFRI; TNFRp55; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type I
Orthologs:
Homo sapiens (human) : TNFRSF1A (TNF receptor superfamily member 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf1a (TNF receptor superfamily member 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf1a (TNF receptor superfamily member 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF1A (TNF receptor superfamily member 1A)
Canis lupus familiaris (dog) : TNFRSF1A (TNF receptor superfamily member 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf1a (TNF receptor superfamily member 1A)
Sus scrofa (pig) : TNFRSF1A (TNF receptor superfamily member 1A)
Chlorocebus sabaeus (African green monkey) : TNFRSF1A (TNF receptor superfamily member 1A)
Heterocephalus glaber (naked mole-rat) : Tnfrsf1a (TNF receptor superfamily member 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6125,349,362 - 125,362,484 (+)Ensembl
GRCm386125,349,723 - 125,362,483 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376125,299,741 - 125,312,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv366125,315,374 - 125,328,104 (+)NCBImm8
Celera6127,020,792 - 127,033,747 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Tnfrsf1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734247
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.