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Gene: Fmo3 (flavin containing monooxygenase 3) Mus musculus
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Symbol: Fmo3
Name: flavin containing monooxygenase 3
Description: Predicted to have N,N-dimethylaniline monooxygenase activity; NADP binding activity; and amino acid binding activity. Predicted to be involved in drug metabolic process. Predicted to localize to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. Is expressed in central nervous system and retina. Orthologous to human FMO3 (flavin containing dimethylaniline monoxygenase 3); PARTICIPATES IN nicotine pharmacodynamics pathway; nicotine pharmacokinetics pathway; tamoxifen pharmacodynamics pathway; INTERACTS WITH 1,2-dichloroethane; 1-naphthyl isothiocyanate; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW111792; dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline oxidase 3; FMO 3; hepatic flavin-containing monooxygenase 3; trimethylamine monooxygenase
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1162,953,800 - 162,984,528 (-)EnsemblGRCm38mm10GRCm38
GRCm381162,953,799 - 162,984,528 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371164,883,931 - 164,914,622 (-)NCBIGRCm37mm9NCBIm37
MGSCv361164,790,475 - 164,821,166 (-)NCBImm8
Celera1165,392,349 - 165,424,291 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fmo3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734271
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.