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Gene: F3 (coagulation factor III) Mus musculus
Symbol: F3
Name: coagulation factor III
Description: Predicted to contribute to serine-type endopeptidase activity. Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of plasma proteins involved in acute inflammatory response; and positive regulation of signal transduction. Predicted to localize to several cellular components, including the cell surface; extracellular space; and serine-type peptidase complex. Human ortholog(s) of this gene implicated in disseminated intravascular coagulation; precursor B lymphoblastic lymphoma/leukemia; and von Willebrand's disease. Is expressed in several structures, including central nervous system; egg cylinder; genitourinary system; gut; and respiratory system. Orthologous to human F3 (coagulation factor III, tissue factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA409063; CD142; Cf-3; Cf3; TF; tissue factor
Homo sapiens (human) : F3 (coagulation factor III, tissue factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : F3 (coagulation factor III, tissue factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F3 (coagulation factor III, tissue factor)
Pan paniscus (bonobo/pygmy chimpanzee) : F3 (coagulation factor III, tissue factor)
Canis lupus familiaris (dog) : F3 (coagulation factor III, tissue factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F3 (coagulation factor III, tissue factor)
Sus scrofa (pig) : F3 (coagulation factor III, tissue factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl3121,723,537 - 121,735,048 (+)Ensembl
GRCm383121,723,537 - 121,735,052 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373121,426,455 - 121,437,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv363121,715,560 - 121,727,066 (+)NCBImm8
Celera3128,097,400 - 128,112,071 (+)NCBICelera
Cytogenetic Map3 G1NCBI
cM Map352.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on F3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734290
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.