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Gene: F3 (coagulation factor III) Mus musculus
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Symbol: F3
Name: coagulation factor III
Description: Predicted to contribute to serine-type endopeptidase activity. Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; activation of plasma proteins involved in acute inflammatory response; and positive regulation of signal transduction. Predicted to localize to several cellular components, including the cell surface; extracellular space; and serine-type peptidase complex. Human ortholog(s) of this gene implicated in disseminated intravascular coagulation; precursor B lymphoblastic lymphoma/leukemia; and von Willebrand's disease. Is expressed in several structures, including central nervous system; egg cylinder; genitourinary system; gut; and respiratory system. Orthologous to human F3 (coagulation factor III, tissue factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA409063; CD142; Cf-3; Cf3; TF; tissue factor
Orthologs:
Homo sapiens (human) : F3 (coagulation factor III, tissue factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : F3 (coagulation factor III, tissue factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F3 (coagulation factor III, tissue factor)
Pan paniscus (bonobo/pygmy chimpanzee) : F3 (coagulation factor III, tissue factor)
Canis lupus familiaris (dog) : F3 (coagulation factor III, tissue factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F3 (coagulation factor III, tissue factor)
Sus scrofa (pig) : F3 (coagulation factor III, tissue factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl3121,723,537 - 121,735,048 (+)Ensembl
GRCm383121,723,537 - 121,735,052 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373121,426,455 - 121,437,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv363121,715,560 - 121,727,066 (+)NCBImm8
Celera3128,097,400 - 128,112,071 (+)NCBICelera
Cytogenetic Map3 G1NCBI
cM Map352.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on F3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734290
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.