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Gene: BCL2L11 (BCL2 like 11) Homo sapiens
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Symbol: BCL2L11
Name: BCL2 like 11
Description: Contributes to microtubule binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of apoptotic process; and response to endoplasmic reticulum stress. Localizes to BIM-BCL-2 complex; BIM-BCL-xl complex; and cytosol. Colocalizes with microtubule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAM; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; bcl-2-like protein 11; bcl-2-related ovarian death agonist; bcl2-interacting mediator of cell death; bcl2-L-11; BCL2-like 11 (apoptosis facilitator); BIM; BIM-alpha6; BIM-beta6; BIM-beta7; BimEL; BimL; BimS; BOD
Orthologs:
Mus musculus (house mouse) : Bcl2l11 (BCL2-like 11 (apoptosis facilitator))  MGI  Alliance
Rattus norvegicus (Norway rat) : Bcl2l11 (BCL2 like 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl2l11 (BCL2 like 11)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL2L11 (BCL2 like 11)
Canis lupus familiaris (dog) : BCL2L11 (BCL2 like 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2l11 (BCL2 like 11)
Sus scrofa (pig) : BCL2L11 (BCL2 like 11)
Chlorocebus sabaeus (African green monkey) : BCL2L11 (BCL2 like 11)
Heterocephalus glaber (naked mole-rat) : Bcl2l11 (BCL2 like 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2111,119,378 - 111,168,445 (+)EnsemblGRCh38hg38GRCh38
GRCh382111,120,914 - 111,168,445 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372111,878,491 - 111,926,022 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362111,594,962 - 111,642,493 (+)NCBINCBI36hg18NCBI36
Build 342111,597,540 - 111,640,814NCBI
Celera2105,529,086 - 105,576,607 (+)NCBI
Cytogenetic Map2q13NCBI
HuRef2104,757,646 - 104,805,166 (+)NCBIHuRef
CHM1_12111,882,732 - 111,930,286 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BCL2L11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734299
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.