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Gene: Serpina5 (serine (or cysteine) peptidase inhibitor, clade A, member 5) Mus musculus
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Symbol: Serpina5
Name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Description: Predicted to have anion binding activity; enzyme binding activity; and serine-type endopeptidase inhibitor activity. Involved in spermatogenesis. Predicted to localize to several cellular components, including the protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and secretory granule. Is expressed in several structures, including epithelium; genitourinary system; gut; musculoskeletal system; and skin. Orthologous to human SERPINA5 (serpin family A member 5); PARTICIPATES IN fibrinolysis pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933415L04; alpha-1 antiproteinase; antitrypsin; PAI-3; PAI3; Pci; plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor-3; protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A, member 5; serpin A5
Orthologs:
Homo sapiens (human) : SERPINA5 (serpin family A member 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpina5 (serpin family A member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpina5 (serpin family A member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINA5 (serpin family A member 5)
Canis lupus familiaris (dog) : LOC480424 (plasma serine protease inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpina5 (serpin family A member 5)
Sus scrofa (pig) : SERPINA5 (serpin family A member 5)
Chlorocebus sabaeus (African green monkey) : SERPINA5 (serpin family A member 5)
Heterocephalus glaber (naked mole-rat) : Serpina5 (serpin family A member 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12104,101,113 - 104,106,137 (+)Ensembl
GRCm3812104,099,313 - 104,106,138 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,339,323 - 105,344,347 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612104,502,163 - 104,507,187 (+)NCBImm8
Celera12105,318,382 - 105,323,416 (+)NCBICelera
Cytogenetic Map12 ENCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serpina5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734302
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.