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Gene: Serpina5 (serine (or cysteine) peptidase inhibitor, clade A, member 5) Mus musculus
Symbol: Serpina5
Name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Description: Predicted to have anion binding activity; enzyme binding activity; and serine-type endopeptidase inhibitor activity. Involved in spermatogenesis. Predicted to localize to several cellular components, including the protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and secretory granule. Is expressed in several structures, including epithelium; genitourinary system; gut; musculoskeletal system; and skin. Orthologous to human SERPINA5 (serpin family A member 5); PARTICIPATES IN fibrinolysis pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933415L04; alpha-1 antiproteinase; antitrypsin; PAI-3; PAI3; Pci; plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor-3; protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A, member 5; serpin A5
Homo sapiens (human) : SERPINA5 (serpin family A member 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpina5 (serpin family A member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpina5 (serpin family A member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINA5 (serpin family A member 5)
Canis lupus familiaris (dog) : LOC480424 (plasma serine protease inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpina5 (serpin family A member 5)
Sus scrofa (pig) : SERPINA5 (serpin family A member 5)
Chlorocebus sabaeus (African green monkey) : SERPINA5 (serpin family A member 5)
Heterocephalus glaber (naked mole-rat) : Serpina5 (serpin family A member 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12104,101,113 - 104,106,137 (+)Ensembl
GRCm3812104,099,313 - 104,106,138 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,339,323 - 105,344,347 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612104,502,163 - 104,507,187 (+)NCBImm8
Celera12105,318,382 - 105,323,416 (+)NCBICelera
Cytogenetic Map12 ENCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Serpina5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734302
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.