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Gene: BMPR1A (bone morphogenetic protein receptor type 1A) Homo sapiens
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Symbol: BMPR1A
Name: bone morphogenetic protein receptor type 1A
CRRD ID: 734372
Description: Exhibits several functions, including ATP binding activity; SMAD binding activity; and protein homodimerization activity. Involved in several processes, including positive regulation of ossification; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and positive regulation of vascular associated smooth muscle cell proliferation. Localizes to external side of plasma membrane. Colocalizes with caveola. Implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Biomarker of pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 10q23del; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK-3; ALK3; BMP type-1A receptor; BMPR-1A; bone morphogenetic protein receptor type IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1a; bone morphogenetic protein receptor, type IA; CD292; serine/threonine-protein kinase receptor R5; SKR5
Orthologs:
Mus musculus (house mouse) : Bmpr1a (bone morphogenetic protein receptor, type 1A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : BMPR1A (bone morphogenetic protein receptor type 1A)
Canis lupus familiaris (dog) : BMPR1A (bone morphogenetic protein receptor type 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Sus scrofa (pig) : BMPR1A (bone morphogenetic protein receptor type 1A)
Chlorocebus sabaeus (African green monkey) : BMPR1A (bone morphogenetic protein receptor type 1A)
Heterocephalus glaber (naked mole-rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)
more info ...
Related Pseudogenes: BMPR1AP1   BMPR1AP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1086,756,601 - 86,932,838 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1086,756,601 - 86,932,825 (+)EnsemblGRCh38hg38GRCh38
GRCh381086,755,786 - 86,927,969 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371088,516,396 - 88,684,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361088,506,376 - 88,674,925 (+)NCBINCBI36hg18NCBI36
Build 341088,506,375 - 88,674,924NCBI
Celera1082,519,484 - 82,687,979 (+)NCBI
Cytogenetic Map10q23.2NCBI
HuRef1082,370,811 - 82,538,774 (+)NCBIHuRef
CHM1_11088,798,078 - 88,966,382 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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