Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Bmpr1a (bone morphogenetic protein receptor, type 1A) Mus musculus
Symbol: Bmpr1a
Name: bone morphogenetic protein receptor, type 1A
CRRD ID: 734373
Description: Exhibits BMP receptor activity. Involved in several processes, including animal organ development; chordate embryonic development; and positive regulation of cell population proliferation. Localizes to cell surface. Predicted to colocalize with caveola. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Ebstein anomaly; Wolff-Parkinson-White syndrome; chromosome 10q23 deletion syndrome; juvenile polyposis syndrome; and osteoarthritis. Human ortholog(s) of this gene implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Orthologous to human BMPR1A (bone morphogenetic protein receptor type 1A); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110037I22Rik; activin receptor-like kinase 3; AL; ALK-3; ALK3; AU045487; Bm; BMP; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; BMPR-1A; BMPR-IA; bone morphogenetic protein receptor type-1A; serine/threonine-protein kinase receptor R5; SKR5
Homo sapiens (human) : BMPR1A (bone morphogenetic protein receptor type 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : BMPR1A (bone morphogenetic protein receptor type 1A)
Canis lupus familiaris (dog) : BMPR1A (bone morphogenetic protein receptor type 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Sus scrofa (pig) : BMPR1A (bone morphogenetic protein receptor type 1A)
Chlorocebus sabaeus (African green monkey) : BMPR1A (bone morphogenetic protein receptor type 1A)
Heterocephalus glaber (naked mole-rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391434,133,018 - 34,225,335 (-)NCBI
GRCm381434,411,061 - 34,503,336 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,410,734 - 34,503,341 (-)EnsemblGRCm38mm10GRCm38
MGSCv371435,224,254 - 35,315,732 (-)NCBIGRCm37mm9NCBIm37
MGSCv361433,240,160 - 33,331,638 (-)NCBImm8
Celera1430,676,409 - 30,725,958 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bmpr1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734373
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.