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Gene: Bmpr1a (bone morphogenetic protein receptor, type 1A) Mus musculus
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Symbol: Bmpr1a
Name: bone morphogenetic protein receptor, type 1A
CRRD ID: 734373
Description: Exhibits BMP receptor activity. Involved in several processes, including animal organ development; chordate embryonic development; and positive regulation of cell population proliferation. Localizes to cell surface. Predicted to colocalize with caveola. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Ebstein anomaly; Wolff-Parkinson-White syndrome; chromosome 10q23 deletion syndrome; juvenile polyposis syndrome; and osteoarthritis. Human ortholog(s) of this gene implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Orthologous to human BMPR1A (bone morphogenetic protein receptor type 1A); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110037I22Rik; activin receptor-like kinase 3; AL; ALK-3; ALK3; AU045487; Bm; BMP; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; BMPR-1A; BMPR-IA; bone morphogenetic protein receptor type-1A; serine/threonine-protein kinase receptor R5; SKR5
Orthologs:
Homo sapiens (human) : BMPR1A (bone morphogenetic protein receptor type 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : BMPR1A (bone morphogenetic protein receptor type 1A)
Canis lupus familiaris (dog) : BMPR1A (bone morphogenetic protein receptor type 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmpr1a (bone morphogenetic protein receptor type 1A)
Sus scrofa (pig) : BMPR1A (bone morphogenetic protein receptor type 1A)
Chlorocebus sabaeus (African green monkey) : BMPR1A (bone morphogenetic protein receptor type 1A)
Heterocephalus glaber (naked mole-rat) : Bmpr1a (bone morphogenetic protein receptor type 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391434,133,018 - 34,225,335 (-)NCBI
GRCm381434,411,061 - 34,503,336 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,410,734 - 34,503,341 (-)EnsemblGRCm38mm10GRCm38
MGSCv371435,224,254 - 35,315,732 (-)NCBIGRCm37mm9NCBIm37
MGSCv361433,240,160 - 33,331,638 (-)NCBImm8
Celera1430,676,409 - 30,725,958 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bmpr1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734373
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.