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Gene: XPNPEP2 (X-prolyl aminopeptidase 2) Homo sapiens
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Symbol: XPNPEP2
Name: X-prolyl aminopeptidase 2
Description: Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AEACEI; aminoacylproline aminopeptidase; APP2; mAmP; membrane-bound aminopeptidase P; membrane-bound AmP; membrane-bound APP; X-Pro aminopeptidase 2; X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound; xaa-Pro aminopeptidase 2
Orthologs:
Mus musculus (house mouse) : Xpnpep2 (X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xpnpep2 (X-prolyl aminopeptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpnpep2 (X-prolyl aminopeptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : XPNPEP2 (X-prolyl aminopeptidase 2)
Canis lupus familiaris (dog) : XPNPEP2 (X-prolyl aminopeptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpnpep2 (X-prolyl aminopeptidase 2)
Sus scrofa (pig) : XPNPEP2 (X-prolyl aminopeptidase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X129,738,970 - 129,769,549 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X128,872,946 - 128,903,525 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X128,700,627 - 128,731,206 (+)NCBINCBI36hg18NCBI36
Build 34X128,598,460 - 128,629,060NCBI
CeleraX129,259,509 - 129,290,027 (+)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX118,278,391 - 118,304,600 (+)NCBIHuRef
CHM1_1X128,784,288 - 128,814,871 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XPNPEP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734376
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.