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Gene: Wnt5a (wingless-type MMTV integration site family, member 5A) Mus musculus
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Symbol: Wnt5a
Name: wingless-type MMTV integration site family, member 5A
Description: Exhibits frizzled binding activity; protein domain specific binding activity; and receptor ligand activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and positive regulation of cytokine production. Localizes to the cell surface and extracellular matrix. Used to study Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; limb; and sensory organ. Orthologous to human WNT5A (Wnt family member 5A); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8030457G12Rik; wingless-related MMTV integration site 5A; Wnt-5a
Orthologs:
Homo sapiens (human) : WNT5A (Wnt family member 5A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wnt5a (Wnt family member 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt5a (Wnt family member 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT5A (Wnt family member 5A)
Canis lupus familiaris (dog) : WNT5A (Wnt family member 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt5a (Wnt family member 5A)
Sus scrofa (pig) : WNT5A (Wnt family member 5A)
Chlorocebus sabaeus (green monkey) : WNT5A (Wnt family member 5A)
Heterocephalus glaber (naked mole-rat) : Wnt5a (Wnt family member 5A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1428,504,750 - 28,527,448 (+)Ensembl
GRCm381428,504,543 - 28,527,448 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371429,318,659 - 29,338,620 (+)NCBIGRCm37mm9NCBIm37
MGSCv361427,332,339 - 27,352,300 (+)NCBImm8
Celera1424,754,276 - 24,774,261 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Wnt5a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734385
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.