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Gene: Folr1 (folate receptor 1 (adult)) Mus musculus
Symbol: Folr1
Name: folate receptor 1 (adult)
Description: Predicted to have carboxylic acid binding activity; folic acid receptor activity; and signaling receptor activity. Involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Predicted to localize to several cellular components, including the anchored component of external side of plasma membrane; basolateral plasma membrane; and brush border membrane. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Is expressed in several structures, including appendicular skeleton; early conceptus; genitourinary system; gut; and nervous system. Orthologous to human FOLR1 (folate receptor alpha); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; endocytosis pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FBP1; folate binding protein 1; folate receptor alpha; folate-binding protein 1; Folbp-1; Folbp1; FR-alpha
Homo sapiens (human) : FOLR1 (folate receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Folr1 (folate receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Folr1 (folate receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : FOLR1 (folate receptor alpha)
Canis lupus familiaris (dog) : FOLR1 (folate receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Folr1 (folate receptor alpha)
Heterocephalus glaber (naked mole-rat) : Folr1 (folate receptor alpha)
more info ...
Related Pseudogenes: Gm18334  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7101,858,331 - 101,870,788 (-)Ensembl
GRCm387101,858,331 - 101,870,788 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377109,006,845 - 109,019,197 (-)NCBIGRCm37mm9NCBIm37
MGSCv367101,732,152 - 101,744,504 (-)NCBImm8
Celera7102,230,147 - 102,242,586 (-)NCBICelera
Cytogenetic Map7 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Folr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734402
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.