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Gene: Folr1 (folate receptor 1 (adult)) Mus musculus
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Symbol: Folr1
Name: folate receptor 1 (adult)
Description: Predicted to have carboxylic acid binding activity; folic acid receptor activity; and signaling receptor activity. Involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Predicted to localize to several cellular components, including the anchored component of external side of plasma membrane; basolateral plasma membrane; and brush border membrane. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Is expressed in several structures, including appendicular skeleton; early conceptus; genitourinary system; gut; and nervous system. Orthologous to human FOLR1 (folate receptor alpha); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; endocytosis pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FBP1; folate binding protein 1; folate receptor alpha; folate-binding protein 1; Folbp-1; Folbp1; FR-alpha
Orthologs:
Homo sapiens (human) : FOLR1 (folate receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Folr1 (folate receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Folr1 (folate receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : FOLR1 (folate receptor alpha)
Canis lupus familiaris (dog) : FOLR1 (folate receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Folr1 (folate receptor alpha)
Heterocephalus glaber (naked mole-rat) : Folr1 (folate receptor alpha)
more info ...
Related Pseudogenes: Gm18334  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl7101,858,331 - 101,870,788 (-)Ensembl
GRCm387101,858,331 - 101,870,788 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377109,006,845 - 109,019,197 (-)NCBIGRCm37mm9NCBIm37
MGSCv367101,732,152 - 101,744,504 (-)NCBImm8
Celera7102,230,147 - 102,242,586 (-)NCBICelera
Cytogenetic Map7 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Folr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734402
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.