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Gene: HCRTR1 (hypocretin receptor 1) Homo sapiens
Symbol: HCRTR1
Name: hypocretin receptor 1
Description: Exhibits orexin receptor activity. Involved in neuropeptide signaling pathway and regulation of cytosolic calcium ion concentration. Localizes to the integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hypocretin (orexin) receptor 1; hypocretin receptor type 1; hypocretin receptor-1; orexin receptor 1; orexin receptor type 1; orexin receptor-1; ox-1-R; ox1-R; OX1R
Mus musculus (house mouse) : Hcrtr1 (hypocretin (orexin) receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hcrtr1 (hypocretin receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcrtr1 (hypocretin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HCRTR1 (hypocretin receptor 1)
Canis lupus familiaris (dog) : HCRTR1 (hypocretin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcrtr1 (hypocretin receptor 1)
Sus scrofa (pig) : HCRTR1 (hypocretin receptor 1)
Chlorocebus sabaeus (African green monkey) : HCRTR1 (hypocretin receptor 1)
Heterocephalus glaber (naked mole-rat) : Hcrtr1 (hypocretin receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl131,617,686 - 31,632,518 (+)EnsemblGRCh38hg38GRCh38
GRCh38131,617,689 - 31,632,518 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37132,083,290 - 32,093,214 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36131,857,228 - 31,865,301 (+)NCBINCBI36hg18NCBI36
Build 34131,753,733 - 31,761,807NCBI
Celera130,352,534 - 30,362,141 (+)NCBI
Cytogenetic Map1p35.2NCBI
HuRef130,200,818 - 30,210,425 (+)NCBIHuRef
CHM1_1132,199,098 - 32,208,715 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HCRTR1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734418
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.