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Gene: Apoa4 (apolipoprotein A-IV) Mus musculus
Symbol: Apoa4
Name: apolipoprotein A-IV
Description: Predicted to have several functions, including cation binding activity; cholesterol binding activity; and cholesterol transfer activity. Involved in innate immune response in mucosa; regulation of intestinal cholesterol absorption; and response to stilbenoid. Localizes to the extracellular space. Predicted to colocalize with the cell surface. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Is expressed in embryo and liver. Orthologous to human APOA4 (apolipoprotein A4); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apo-AIV; Apoa-4; apoA-IV; apolipoprotein A4
Homo sapiens (human) : APOA4 (apolipoprotein A4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apoa4 (apolipoprotein A4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoa4 (apolipoprotein A4)
Pan paniscus (bonobo/pygmy chimpanzee) : APOA4 (apolipoprotein A4)
Canis lupus familiaris (dog) : APOA4 (apolipoprotein A4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoa4 (apolipoprotein A4)
Sus scrofa (pig) : APOA4 (apolipoprotein A4)
Chlorocebus sabaeus (African green monkey) : APOA4 (apolipoprotein A4)
Heterocephalus glaber (naked mole-rat) : Apoa4 (apolipoprotein A4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl946,240,696 - 46,243,459 (+)Ensembl
GRCm38946,240,844 - 46,243,458 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37946,048,927 - 46,051,541 (+)NCBIGRCm37mm9NCBIm37
MGSCv36945,992,149 - 45,994,285 (+)NCBImm8
Celera943,529,774 - 43,532,388 (+)NCBICelera
Cytogenetic Map9 A5.2NCBI
cM Map925.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Apoa4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734420
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.