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Gene: CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit) Homo sapiens
Symbol: CHRNA5
Name: cholinergic receptor nicotinic alpha 5 subunit
Description: Exhibits acetylcholine receptor activity. Predicted to contribute to acetylcholine binding activity. Involved in behavioral response to nicotine. Predicted to localize to acetylcholine-gated channel complex; neuron projection; and synapse. Implicated in lung cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acetylcholine receptor, nicotinic, alpha 5 (neuronal); Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5; cholinergic receptor, nicotinic alpha 5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; LNCR2; neuronal acetylcholine receptor subunit alpha-5; neuronal nicotinic acetylcholine receptor, alpha5 subunit
Mus musculus (house mouse) : Chrna5 (cholinergic receptor, nicotinic, alpha polypeptide 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Canis lupus familiaris (dog) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)
Sus scrofa (pig) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Heterocephalus glaber (naked mole-rat) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1578,565,520 - 78,595,269 (+)EnsemblGRCh38hg38GRCh38
GRCh381578,565,520 - 78,595,269 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371578,857,862 - 78,887,611 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,644,961 - 76,673,515 (+)NCBINCBI36hg18NCBI36
Build 341576,644,960 - 76,673,513NCBI
Celera1555,794,174 - 55,823,924 (+)NCBI
Cytogenetic Map15q25.1NCBI
HuRef1555,614,929 - 55,644,700 (+)NCBIHuRef
CHM1_11578,976,380 - 79,006,179 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHRNA5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734445
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.