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Gene: Rheb (Ras homolog enriched in brain) Mus musculus
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Symbol: Rheb
Name: Ras homolog enriched in brain
Description: Exhibits GTP binding activity and protein kinase binding activity. Involved in negative regulation of cold-induced thermogenesis; positive regulation of TOR signaling; and positive regulation of oligodendrocyte differentiation. Localizes to spliceosomal complex. Is expressed in chondrocranium bone; nervous system; nucleus pulposus; and sensory organ. Orthologous to human RHEB (Ras homolog, mTORC1 binding); PARTICIPATES IN mTOR signaling pathway; Rheb mediated signaling pathway; insulin signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GTP-binding protein Rheb; RAS-homolog enriched in brain; Rheb1
Orthologs:
Homo sapiens (human) : RHEB (Ras homolog, mTORC1 binding)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rheb (Ras homolog, mTORC1 binding)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rheb (Ras homolog, mTORC1 binding)
Pan paniscus (bonobo/pygmy chimpanzee) : RHEB (Ras homolog, mTORC1 binding)
Canis lupus familiaris (dog) : RHEB (Ras homolog, mTORC1 binding)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rheb (Ras homolog, mTORC1 binding)
Sus scrofa (pig) : RHEB (Ras homolog, mTORC1 binding)
Chlorocebus sabaeus (African green monkey) : RHEB (Ras homolog, mTORC1 binding)
Heterocephalus glaber (naked mole-rat) : Rheb (Ras homolog, mTORC1 binding)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl524,802,823 - 24,842,624 (-)EnsemblGRCm38mm10GRCm38
GRCm38524,802,823 - 24,842,361 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37524,308,641 - 24,348,179 (-)NCBIGRCm37mm9NCBIm37
MGSCv36524,312,888 - 24,352,426 (-)NCBImm8
Celera521,753,578 - 21,793,634 (-)NCBICelera
Cytogenetic Map5A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rheb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 734450
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.