Gene: RT1-S3 (RT1 class Ib, locus S3) Rattus norvegicus
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Symbol: RT1-S3
Name: RT1 class Ib, locus S3
Description: Predicted to have beta-2-microglobulin binding activity, peptide antigen binding activity, and signaling receptor binding activity; predicted to be involved in several processes, including defense response to bacterium, positive regulation of cytokine production, and positive regulation of immune effector process; predicted to localize to the MHC protein complex, external side of plasma membrane, and extracellular space; orthologous to human HLA-E (major histocompatibility complex, class I, E); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BM1; BM1av1; H2-T23; histocompatibility 2, T region locus 23; MHC class Ib RT1.S3; RT-BM1; RT1 class Ib gene(BM!); RT1 class Ib, locus BM1; RT1-BM1; RT1.S3; RTBM1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,176,124 - 3,180,825 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0205,274,209 - 5,278,991 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4202,815,943 - 2,820,644 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1202,816,244 - 2,820,867 (+)NCBI
Celera20101,124 - 105,825 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on RT1-S3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735037
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.