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Gene: Nme8 (NME/NM23 family member 8) Rattus norvegicus
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Symbol: Nme8
Name: NME/NM23 family member 8
Description: Predicted to have microtubule binding activity. Predicted to be involved in cellular response to reactive oxygen species; cilium assembly; and flagellated sperm motility. Localizes to the sperm fibrous sheath. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to human NME8 (NME/NM23 family member 8); INTERACTS WITH bisphenol A; trichloroethene; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: spermatid-specific thioredoxin-2 protein; sptrx-2; Sptrx2; thioredoxin domain containing 3; thioredoxin domain containing 3 (spermatozoa); thioredoxin domain-containing protein 3; Txndc3
Orthologs:
Homo sapiens (human) : NME8 (NME/NM23 family member 8)  HGNC  Alliance
Mus musculus (house mouse) : Nme8 (NME/NM23 family member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nme8 (NME/NM23 family member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : NME8 (NME/NM23 family member 8)
Canis lupus familiaris (dog) : NME8 (NME/NM23 family member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nme8 (NME/NM23 family member 8)
Sus scrofa (pig) : NME8 (NME/NM23 family member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01747,300,932 - 47,368,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01756,120,328 - 56,185,444 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41753,037,090 - 53,105,985 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11753,040,678 - 53,108,823 (+)NCBI
Celera1751,224,029 - 51,290,939 (-)NCBICelera
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nme8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735069
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.