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Gene: Nme8 (NME/NM23 family member 8) Rattus norvegicus
Symbol: Nme8
Name: NME/NM23 family member 8
Description: Predicted to have microtubule binding activity. Predicted to be involved in cellular response to reactive oxygen species; cilium assembly; and flagellated sperm motility. Localizes to the sperm fibrous sheath. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to human NME8 (NME/NM23 family member 8); INTERACTS WITH bisphenol A; trichloroethene; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: spermatid-specific thioredoxin-2 protein; sptrx-2; Sptrx2; thioredoxin domain containing 3; thioredoxin domain containing 3 (spermatozoa); thioredoxin domain-containing protein 3; Txndc3
Homo sapiens (human) : NME8 (NME/NM23 family member 8)  HGNC  Alliance
Mus musculus (house mouse) : Nme8 (NME/NM23 family member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nme8 (NME/NM23 family member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : NME8 (NME/NM23 family member 8)
Canis lupus familiaris (dog) : NME8 (NME/NM23 family member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nme8 (NME/NM23 family member 8)
Sus scrofa (pig) : NME8 (NME/NM23 family member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01747,300,932 - 47,368,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01756,120,328 - 56,185,444 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41753,037,090 - 53,105,985 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11753,040,678 - 53,108,823 (+)NCBI
Celera1751,224,029 - 51,290,939 (-)NCBICelera
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Nme8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735069
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.