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Gene: Megf10 (multiple EGF-like domains 10) Rattus norvegicus
Symbol: Megf10
Name: multiple EGF-like domains 10
CRRD ID: 735084
Description: Predicted to have Notch binding activity; complement component C1q complex binding activity; and scavenger receptor activity. Predicted to be involved in several processes, including apoptotic cell clearance; myoblast migration; and skeletal muscle satellite cell proliferation. Predicted to localize to phagocytic cup. Human ortholog(s) of this gene implicated in early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: multiple epidermal growth factor-like domains protein 10
Homo sapiens (human) : MEGF10 (multiple EGF like domains 10)  HGNC  Alliance
Mus musculus (house mouse) : Megf10 (multiple EGF-like-domains 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Megf10 (multiple EGF like domains 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MEGF10 (multiple EGF like domains 10)
Canis lupus familiaris (dog) : MEGF10 (multiple EGF like domains 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Megf10 (multiple EGF like domains 10)
Sus scrofa (pig) : MEGF10 (multiple EGF like domains 10)
Chlorocebus sabaeus (African green monkey) : MEGF10 (multiple EGF like domains 10)
Heterocephalus glaber (naked mole-rat) : Megf10 (multiple EGF like domains 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01852,215,652 - 52,366,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1852,215,682 - 52,366,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01851,403,811 - 51,554,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,948,935 - 53,051,823 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11853,052,380 - 53,072,113 (+)NCBI
Celera1848,786,696 - 48,889,249 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Megf10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735084
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.