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Gene: Prickle1 (prickle planar cell polarity protein 1) Rattus norvegicus
Symbol: Prickle1
Name: prickle planar cell polarity protein 1
CRRD ID: 735090
Description: Exhibits transcription factor binding activity. Involved in protein import into nucleus. Predicted to localize to cytosol and nuclear membrane. Used to study temporal lobe epilepsy. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; Wnt signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
Also known as: prickle homolog 1; prickle homolog 1 (Drosophila); prickle-like 1; prickle-like 1 (Drosophila); prickle-like protein 1; REST/NRSF-interacting lim domain protein; REST/NRSF-interacting LIM domain protein 1; Rilp
Homo sapiens (human) : PRICKLE1 (prickle planar cell polarity protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Prickle1 (prickle planar cell polarity protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prickle1 (prickle planar cell polarity protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRICKLE1 (prickle planar cell polarity protein 1)
Canis lupus familiaris (dog) : PRICKLE1 (prickle planar cell polarity protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prickle1 (prickle planar cell polarity protein 1)
Sus scrofa (pig) : PRICKLE1 (prickle planar cell polarity protein 1)
Chlorocebus sabaeus (African green monkey) : PRICKLE1 (prickle planar cell polarity protein 1)
Heterocephalus glaber (naked mole-rat) : Prickle1 (prickle planar cell polarity protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07134,702,964 - 134,799,437 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7134,702,964 - 134,722,215 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07134,370,195 - 134,466,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47131,967,220 - 131,986,187 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17132,044,813 - 132,052,370 (-)NCBI
Celera7121,036,572 - 121,055,537 (-)NCBICelera
Cytogenetic Map7q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Prickle1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735090
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.