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Gene: Sil1 (SIL1 nucleotide exchange factor) Rattus norvegicus
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Symbol: Sil1
Name: SIL1 nucleotide exchange factor
Description: Predicted to have adenyl-nucleotide exchange factor activity. Predicted to be involved in protein transport and regulation of catalytic activity. Predicted to localize to the endoplasmic reticulum. Human ortholog(s) of this gene implicated in primary cerebellar degeneration. Orthologous to human SIL1 (SIL1 nucleotide exchange factor); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,5-hexanedione; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae); MGC72590; nucleotide exchange factor SIL1; SIL1 homolog, endoplasmic reticulum chaperone; SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae); similar to endoplasmic reticulum chaperone SIL1 homolog
Orthologs:
Homo sapiens (human) : SIL1 (SIL1 nucleotide exchange factor)  HGNC  Alliance
Mus musculus (house mouse) : Sil1 (endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sil1 (SIL1 nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SIL1 (SIL1 nucleotide exchange factor)
Canis lupus familiaris (dog) : SIL1 (SIL1 nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sil1 (SIL1 nucleotide exchange factor)
Sus scrofa (pig) : SIL1 (SIL1 nucleotide exchange factor)
Chlorocebus sabaeus (green monkey) : SIL1 (SIL1 nucleotide exchange factor)
Heterocephalus glaber (naked mole-rat) : Sil1 (SIL1 nucleotide exchange factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01828,067,476 - 28,302,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,067,484 - 28,301,863 (-)Ensembl
Rnor_5.01827,777,570 - 28,015,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,780,878 - 27,957,033 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11827,807,524 - 27,983,675 (-)NCBI
Celera1826,607,704 - 26,838,633 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sil1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735103
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.