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Gene: Slc4a8 (solute carrier family 4 member 8) Rattus norvegicus
Symbol: Slc4a8
Name: solute carrier family 4 member 8
Description: Predicted to have sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport and regulation of intracellular pH. Predicted to localize to the integral component of plasma membrane; neuron projection; and neuronal cell body membrane. Biomarker of prediabetes syndrome. Orthologous to human SLC4A8 (solute carrier family 4 member 8); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: electroneutral Na+-driven Cl-HCO3 exchanger; electroneutral sodium bicarbonate exchanger 1; k-NBC3; LOC315311; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; solute carrier family 4 (anion exchanger), member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
Homo sapiens (human) : SLC4A8 (solute carrier family 4 member 8)  HGNC  Alliance
Mus musculus (house mouse) : Slc4a8 (solute carrier family 4 (anion exchanger), member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a8 (solute carrier family 4 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A8 (solute carrier family 4 member 8)
Canis lupus familiaris (dog) : SLC4A8 (solute carrier family 4 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a8 (solute carrier family 4 member 8)
Sus scrofa (pig) : SLC4A8 (solute carrier family 4 member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,397,352 - 142,467,398 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07140,201,544 - 140,271,679 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,230,085 - 139,575,631 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17139,306,521 - 139,652,068 (+)NCBI
Celera7128,340,100 - 128,399,333 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Slc4a8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735164
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.