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Gene: Zfyve27 (zinc finger FYVE-type containing 27) Rattus norvegicus
Symbol: Zfyve27
Name: zinc finger FYVE-type containing 27
Description: Predicted to have protein self-association. Involved in neuron projection development; neurotrophin TRK receptor signaling pathway; and protein localization to plasma membrane. Localizes to the growth cone membrane and recycling endosome membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 33. Orthologous to human ZFYVE27 (zinc finger FYVE-type containing 27); INTERACTS WITH (RS)-amphetamine; 2,4-dinitrotoluene; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC72597; protrudin; Unknown (protein for MGC:72597); zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27
Homo sapiens (human) : ZFYVE27 (zinc finger FYVE-type containing 27)  HGNC  Alliance
Mus musculus (house mouse) : Zfyve27 (zinc finger, FYVE domain containing 27)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zfyve27 (zinc finger FYVE-type containing 27)
Pan paniscus (bonobo/pygmy chimpanzee) : ZFYVE27 (zinc finger FYVE-type containing 27)
Canis lupus familiaris (dog) : ZFYVE27 (zinc finger FYVE-type containing 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zfyve27 (zinc finger FYVE-type containing 27)
Sus scrofa (pig) : ZFYVE27 (zinc finger FYVE-type containing 27)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01261,415,172 - 261,438,539 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01268,867,649 - 268,891,011 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41248,663,072 - 248,683,668 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11248,922,982 - 248,943,578 (-)NCBI
Celera1236,814,158 - 236,837,503 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Zfyve27
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735177
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.