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Gene: Acvr1b (activin A receptor type 1B) Rattus norvegicus
Symbol: Acvr1b
Name: activin A receptor type 1B
Description: Predicted to contribute to activin-activated receptor activity and growth factor binding activity. Involved in central nervous system development; development of primary female sexual characteristics; and positive regulation of nitrogen compound metabolic process. Predicted to localize to activin receptor complex; cell surface; and cytosol. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ACVR1B (activin A receptor type 1B); PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: activin A receptor, type 1B; activin A receptor, type IB; activin receptor type IB; activin receptor type-1B; activin receptor-like kinase 4; ACTR-IB; ALK-4; Serine/threonine-protein kinase receptor R2; Serine/threonine-protein kinase receptor R2 precursor; Skr2
Homo sapiens (human) : ACVR1B (activin A receptor type 1B)  HGNC  Alliance
Mus musculus (house mouse) : Acvr1b (activin A receptor, type 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr1b (activin A receptor type 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR1B (activin A receptor type 1B)
Canis lupus familiaris (dog) : ACVR1B (activin A receptor type 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr1b (activin A receptor type 1B)
Sus scrofa (pig) : ACVR1B (activin A receptor type 1B)
Chlorocebus sabaeus (African green monkey) : ACVR1B (activin A receptor type 1B)
Heterocephalus glaber (naked mole-rat) : Acvr1b (activin A receptor type 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,817,174 - 142,858,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,817,157 - 142,860,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,617,642 - 140,659,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,910,157 - 139,958,740 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,015,437 - 140,035,177 (+)NCBI
Celera7128,775,059 - 128,793,132 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Acvr1b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735207
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.