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Gene: Serping1 (serpin family G member 1) Rattus norvegicus
Symbol: Serping1
Name: serpin family G member 1
Description: Predicted to have complement binding activity and serine-type endopeptidase inhibitor activity. Involved in aging. Localizes to extracellular space. Used to study glioblastoma multiforme. Biomarker of acute myocardial infarction. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebral infarction; macular degeneration; pancreatitis; and toxic shock syndrome. Orthologous to human SERPING1 (serpin family G member 1); PARTICIPATES IN coagulation cascade pathway; kallikrein-kinin cascade pathway; complement system pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
Also known as: C1 esterase inhibitor; C1 Inh; C1-IA; C1-inactivator; C1-inhibiting factor; C1Inh; MGC72585; plasma protease C1 inhibitor; serine (or cysteine) peptidase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); serpin G1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; serpin peptidase inhibitor, clade G, member 1
Homo sapiens (human) : SERPING1 (serpin family G member 1)  HGNC  Alliance
Mus musculus (house mouse) : Serping1 (serine (or cysteine) peptidase inhibitor, clade G, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serping1 (serpin family G member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPING1 (serpin family G member 1)
Canis lupus familiaris (dog) : SERPING1 (serpin family G member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serping1 (serpin family G member 1)
Sus scrofa (pig) : SERPING1 (serpin family G member 1)
Chlorocebus sabaeus (African green monkey) : SERPING1 (serpin family G member 1)
Heterocephalus glaber (naked mole-rat) : Serping1 (serpin family G member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0372,161,230 - 72,171,109 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,161,189 - 72,171,078 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,681,813 - 78,691,622 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,968,808 - 67,978,102 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1367,865,179 - 67,874,474 (-)NCBI
Celera369,198,069 - 69,207,363 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Serping1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735225
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.