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Gene: ALDH5A1 (aldehyde dehydrogenase 5 family member A1) Homo sapiens
Symbol: ALDH5A1
Name: aldehyde dehydrogenase 5 family member A1
Description: Exhibits succinate-semialdehyde dehydrogenase (NAD+) activity. Involved in central nervous system development; gamma-aminobutyric acid catabolic process; and protein homotetramerization. Localizes to the mitochondrion. Implicated in succinic semialdehyde dehydrogenase deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase); aldehyde dehydrogenase family 5 member A1; aldehyde dehydrogenase family 5, subfamily a1; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; SSADH; SSDH; succinate-semialdehyde dehydrogenase, mitochondrial
Mus musculus (house mouse) : Aldh5a1 (aldhehyde dehydrogenase family 5, subfamily A1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aldh5a1 (aldehyde dehydrogenase 5 family, member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldh5a1 (aldehyde dehydrogenase 5 family member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH5A1 (aldehyde dehydrogenase 5 family member A1)
Canis lupus familiaris (dog) : ALDH5A1 (aldehyde dehydrogenase 5 family member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh5a1 (aldehyde dehydrogenase 5 family member A1)
Sus scrofa (pig) : ALDH5A1 (aldehyde dehydrogenase 5 family member A1)
Chlorocebus sabaeus (African green monkey) : ALDH5A1 (aldehyde dehydrogenase 5 family member A1)
Heterocephalus glaber (naked mole-rat) : Aldh5a1 (aldehyde dehydrogenase 5 family member A1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl624,494,867 - 24,537,207 (+)EnsemblGRCh38hg38GRCh38
GRCh38624,494,969 - 24,537,207 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37624,495,197 - 24,537,435 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,603,176 - 24,645,414 (+)NCBINCBI36hg18NCBI36
Build 34624,603,175 - 24,645,414NCBI
Celera625,728,607 - 25,770,806 (+)NCBI
Cytogenetic Map6p22.3NCBI
HuRef624,444,647 - 24,486,850 (+)NCBIHuRef
CHM1_1624,499,400 - 24,541,589 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ALDH5A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735245
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.