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Gene: GPR37 (G protein-coupled receptor 37) Homo sapiens
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Symbol: GPR37
Name: G protein-coupled receptor 37
Description: Exhibits several functions, including G protein-coupled receptor activity; Hsp70 protein binding activity; and ubiquitin protein ligase binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and positive regulation of MAPK cascade. Localizes to several cellular components, including the endoplasmic reticulum; receptor complex; and ubiquitin ligase complex. Biomarker of Lewy body dementia and Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EDNRBL; endothelin B receptor-like protein 1; endothelin receptor type B-like; ETBR-LP-1; G protein-coupled receptor 37 (endothelin receptor type B-like); G-protein coupled receptor 37; hET(B)R-LP; PAELR; Parkin-associated endothelin receptor-like receptor; probable G-protein coupled receptor 37; prosaposin receptor GPR37
Orthologs:
Mus musculus (house mouse) : Gpr37 (G protein-coupled receptor 37)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr37 (G protein-coupled receptor 37)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr37 (G protein-coupled receptor 37)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR37 (G protein-coupled receptor 37)
Canis lupus familiaris (dog) : GPR37 (G protein-coupled receptor 37)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr37 (G protein-coupled receptor 37)
Sus scrofa (pig) : GPR37 (G protein-coupled receptor 37)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387124,743,885 - 124,765,792 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377124,385,655 - 124,406,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367124,173,350 - 124,192,917 (-)NCBINCBI36hg18NCBI36
Build 347123,980,066 - 123,999,632NCBI
Celera7119,191,362 - 119,210,932 (-)NCBI
Cytogenetic Map7q31.33NCBI
HuRef7118,750,711 - 118,771,098 (-)NCBIHuRef
CHM1_17124,318,797 - 124,339,217 (-)NCBICHM1_1
CRA_TCAGchr7v27123,775,046 - 123,795,470 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GPR37
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735262
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.